Concentration Details

Metabolite
HMDB0000253 (Pregnenolone)
Biospecimen
Blood
Status
Detected and Quantified
Data source
Referenced
Concentration
0.00974 +/- 0.00371 uM
Age
Adult (>18 years old)
Sex
Female
Condition
Postpartum depression
Comments
n=5, 2-7 days postpartum with symptoms of the "blues"
References
    1. Pearson Murphy BE, Steinberg SI, Hu FY, Allison CM: Neuroactive ring A-reduced metabolites of progesterone in human plasma during pregnancy: elevated levels of 5 alpha-dihydroprogesterone in depressed patients during the latter half of pregnancy. J Clin Endocrinol Metab. 2001 Dec;86(12):5981-7. [PubMed:11739473 ]